David Moyes took over as coach of the Basque club last month and has presided over a draw and a win in La Liga, as well as the stalemate in Oviedo which gave Sociedad a slight advantage ahead of the return in San Sebastian in two weeks.Villarreal have one foot in the last 16 after they held on with nine men for a 2-1 success at third-tier Cadiz.
Defender Adrian Marin was shown a straight red card in the 59th minute and Israel Puerto was forced off due to injury when Villarreal had already used up their three substitutions.
Valencia were to play at Rayo Vallecano later on Thursday in one of only four last-32 ties featuring two clubs from the Spanish top flight.
Holders Real Madrid and 2010 winners Sevilla are through to the last 16 after completing crushing aggregate wins against third-tier Cornella and second-division Sabadell respectively.
Both ties were brought forward because of Real’s participation in the Club World Cup and the resulting disruption to the La Liga calendar caused by this month’s tournament in Morocco.
Real are almost certain to meet Atletico Madrid after the La Liga champions, who beat their city rivals 2-1 after extra time in the 2013 Cup final, won their last-32, first leg 3-0 at third-tier Hospitalet on Wednesday.
In French Football, Lyon moved back into third place in the French league after Alexandre Lacazette scored the winning goal in a 2-1 defeat of Reims on Thursday.
Lacazette fired into the top corner from a tight angle in the first minute of stoppage time, notching his 12th league goal this season to consolidate his spot as the top scorer.
Lyon midfielder Corentin Tolisso opened the scoring with a close-range header in the sixth minute, then Reims winger Benjamin Moukandjo levelled by converting a rebound in the 36th.
Lyon took the lead when Tolisso headed in a free-kick from Fekir, who nearly scored a wonder goal with a 50-yard lob that Reims goalkeeper Johny Placide stopped in the 35th.
However, the hosts invited Reims pressure by sitting back to protect their lead. Lyon goalkeeper Anthony Lopes parried a long-range strike from Prince Oniangue but could not prevent Moukandjo from volleying the rebound home.
Lyon played with more desire in the second half but was let down by some poor finishing from Fekir in the 48th, Mohamed Yattara in the 57th, and Jordan Ferri in the 78th, until Placide palmed into his own net Lacazette’s drive from the by-line.